Strand 2: Understanding bivalve functional response for alternative methods of prevention and treatment

The objective of this 2nd axis is to improve knowledge about the physiological functions that allow the animals to resist to the diseases. What are the response mechanisms used by the animals to survive? How do the surrounding pathogens interact with the animals? To sum up, we aim to understand better what makes a farmed shell resist microbe aggressions.

This working group aims to advance and consolidate the available knowledge on the identification and characterization of gene and gene networks mediating the interaction between bivalves and pathogens together with multiple environmental stressors as well as determining the virulence mechanisms used by pathogens, in controlled conditions. The final goal is to understand what triggers disease and mortality enabling the development of tools and processes directly transferable to the bivalve production industry.
Approach:

  • Focus on the molecular basis of resistance to pathogens including characterisation of phenotypically diverse bivalves presenting contrasting susceptibility to pathogens
  • Understanding virulence and pathogenesis in controlled conditions
  • Exploring pathogen interactions in controlled conditions
  • Developing new approaches to stimulate bivalve immunity

Main expected result:

  • Developing new approaches to stimulate bivalve immunity