Strand 3: Genetic solutions for disease resistance / tolerance

The objective of this 3rd axis is to develop disease-resistant oysters and clams, while maintaining the highest possible genetic diversity. The potential impact of genetic selection will also be explored.

Selective breeding for disease resistance and tolerance represents an alternative that can secure a sustainable, long-term reduction of production losses. WP3 will focus on viral and bacterial pathogens affecting the Pacific cupped oyster (OsHV-1, V. aestuarianus and V. splendidus) in addition to parasites affecting the European flat oyster (B. ostraeae) and pathogens affecting the Manila clam (V. tapetis and P. olseni).


  • Estimating genetic parameters for disease resistance or tolerance and their genetic correlations with production trait and quality traits
  • Development of genomic tools to initiate marker assisted selection or genomic selection for disease tolerance/resistance.
  • Design of breeding programmes for implementation by SMEs
  • Characterization of diversity and allele frequencies in candidate genes associated with survival

Main expected deliverables:

  • Identification of genetic parameters for disease resistance or tolerance
  • Design of breeding programmes