Italian and French researchers involved in VIVALDI have published 3 articles emphasising some first scientific results partially obtained thanks to our project.
Manuscript: Adsorption of norovirus and ostreid herpesvirus type 1 to polymer membranes for the development of passive samplers (Hubert Francoise, Morga Benjamin, Renault Tristan, Le Guyader Soizick)
Published in the Journal of Applied Microbiology, 2017, http://doi.org/10.1111/jam.13394
VIVALDI partner involved: IFREMER (FR)
Ifremer researchers detailed the development of passive sensors aiming at detecting the OsHV-1 virus or norovirus. These sensors have been elaborated in laboratory conditions. They are currently being tested in the natural environment.
Manuscript: cDNA and Gene Structure of MytiLec-1, A Bacteriostatic R-Type Lectin from the Mediterranean Mussel (Mytilus galloprovincialis)
Published on Marine Drugs, 2016, https://dx.doi.org/10.3390%2Fmd14050092
VIVALDI partner involved: UNITS (IT)
A novel class of proteins has been found in mussels (Mytilus spp.) in 2012. Since then, MytiLec has attracted a considerable scientific interest due to a property which could be potentially exploited for biotechnological and therapeutic applications. This paper reports for the first mytilectins as a multi-genic gene family, which could be effectively used for defense in response to pathogen infections. Moreover, it was demonstrated that MytiLec may have a role in microbial recognition and killing.
Manuscript: Diversity and evolution of TIR-domain-containing proteins in bivalves and Metazoa: New insights from comparative genomics
Published on Developmental and Comparative Immunology, 2017, http://dx.doi.org/10.1016/j.dci.2017.01.014
VIVALDI partners involved: UNITS, UNIPD (IT)
A comparative analysis of bivalve genomes has allowed identifying 14 novel TIR-DC protein families. These proteins are known to play a key role in the regulation of the inflammatory response and the production of antimicrobial effectors.